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br Introduction Localized degenerative and progressive enlar
2019-11-21
Introduction Localized, degenerative and progressive enlargement of the aortic diameter involves all layers of the vessel wall may ultimately rupture creating a catastrophic cardiovascular event [1,2]. An aneurysm may be located in the thoracic or abdominal aortic wall with different clinical app
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Cryoprotectant equilibration and the response to ice concent
2019-11-21
Cryoprotectant equilibration and the response to ice concentrated media are the two facets of cellular cryobiological protocols most commonly covered by mathematical modeling. In these models, monensin are typically assumed to have uniform, spatially independent extracellular concentrations and tem
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Fig shows graphically the abundance
2019-11-21
Fig. 3 shows, graphically, the abundance distributions of the ARD% of the investigated data with both the CPA-NRTL and CPA-UNIQUAC models, where ARD% is defined as,in which x and x are the experimental and calculated SO2 molar compositions in the liquid phase, respectively, and N is the total number
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In we studied normal rational varieties X of complexity
2019-11-21
In [1] we studied normal, rational -varieties X of complexity one, where the latter means that X comes with an effective torus action such that holds. We showed that for affine X with and at most log terminal singularities, the iteration of Cox rings is possible. In the present article, we character
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Recently it was reported that Crm is
2019-11-21
Recently, it was reported that Crm1 is linked to spindle pole body (SPB) by Spc72 in SC75741 sale yeast [9]. Spc72 and Spc110 are two specific receptors of γ-tubulin complex (Tub4), which target Tub4 to SPB and mediate the nucleation of microtubules from SPB [20]. It was found that disrupting the i
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Previously published results on this topic are inconsistent
2019-11-21
Previously published results on this topic are inconsistent. Stressin1-A, a novel CRF1 receptor agonist, increased anxiety-like behavior in the social interaction and shock-probe tests [51]. Pharmacological blockade of CRF1 (NBI-30775) reversed both CRF-induced increases in startle and CRF-induced d
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Our results indicate that C
2019-11-21
Our results indicate that C75-CoA is formed in the hypothalamus following stereotaxic injection of C75. Inhibition of hypothalamic CPT1 by C75-CoA in vivo, as seen in our experiments, is independent of the putative inhibition by malonyl-CoA, which may be formed after the action of C75 either on FAS
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Another interesting finding regarding substrate selectivity
2019-11-20
Another interesting finding regarding substrate selectivity of iPLA2-VIA in whole cellular systems stems from the observation that some of the major species hydrolyzed by the enzyme contain a 16:1 fatty Carmofur mg at the sn-2 position [57,119], raising the possibility that iPLA2-VIA may constitute
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br The contribution of Interference RNA and epigenetic
2019-11-20
The contribution of Interference RNA and epigenetic in OA attenuation Interference RNA, a cellular mechanism for post-transcriptional gene silencing that is associated with mRNA. The potential of RNAi has successfully silenced the wide range of protein coding genes. Its high specificity sanctions
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Structural changes within the heteromer induced by
2019-11-20
Structural changes within the heteromer induced by agonist administration show a high level of complication. The presented results obtained in quantitative FLIM-FRET measurements with two selective ligands match the qualitative conclusions indicated by changes in the intracellular calcium level. The
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Among prostaglandins PG PGD remained
2019-11-20
Among prostaglandins (PG), PGD2 remained the most elusive species for a long time and was initially regarded as having negligible biological activity [1]. In 1974 its inhibitory effect on platelet aggregation was discovered by Smith et al. [2] and Mills & McFarlain [3], and both pressor and depresso
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This review focuses on the atomic basis of CRM
2019-11-20
This review focuses on the atomic basis of CRM1-mediated nuclear export. There are now 27 crystal structures of CRM1 in the Protein Data Bank (PDB) (www.rcsb.org) [64]. Collectively, this large body of work explains various aspects of CRM1 function. Here we summarize the structure–function studies t
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br Involvement of p MAPK pathway
2019-11-20
Involvement of p38 MAPK pathway The NF-κB signal transduction cascade is a major stress response signaling pathway for the COX-2 gene expression. In mice and humans, the COX-2 promoter has PD 169316 for many transcription factors, including NF-κB in the 5′ region of the COX-2 gene [11], and the
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br Materials and methods br Results br
2019-11-20
Materials and methods Results Discussion In this study, the N&B analysis showed new evidence regarding the proportion and the oligomerization state of the AT1 and the ETA receptors near or on the plasma membrane. Althought, preliminary studies suggest that the AT1 and the ETA receptors occu
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For membrane protected SPE the choice
2019-11-20
For membrane protected μ-SPE, the choice of sorbent is crucial because it determines the extraction efficiency. Up to now, many porous materials, such as carbon based sorbents [1,[3], [4], [5], [6]], ethylsilane or octadecylsilane modified silica (C2 or C18) [7,8], polymeric materials [[9], [10], [1
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